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| 文獻(xiàn)摘要：膳食攝入的類胡蘿卜素在心血管保健上的抗氧化和抗炎癥作用 |
| 發(fā)布時(shí)間：2015/12/8 13:47:21 閱讀次數(shù)：264 |
當(dāng)前，以動(dòng)脈硬化為代表的心血管疾病在發(fā)達(dá)國(guó)家有最高的發(fā)病率和致死率。鑒于動(dòng)脈硬化產(chǎn)生炎癥的特質(zhì)，已經(jīng)開(kāi)展了動(dòng)脈壁抗炎活性物質(zhì)的發(fā)掘工作，這些物質(zhì)能夠能夠?qū)】诞a(chǎn)生有益的作用。由于類胡羅卜素能夠清除自由基、提高低密度脂蛋白膽固醇的抗氧化作用，因此一些文章研究了膳食補(bǔ)充類胡羅卜素對(duì)心血管疾病的作用。不過(guò)，文獻(xiàn)資料卻相互矛盾：盡管一些研究發(fā)現(xiàn)膳食補(bǔ)充類胡羅卜素與降低心血管疾病有正相關(guān)的關(guān)系，但是其它研究并沒(méi)有發(fā)現(xiàn)二者之間有任何的正相關(guān)性，甚至一些研究還發(fā)現(xiàn)類胡羅卜素具有促進(jìn)氧化的作用。本文旨在通過(guò)文獻(xiàn)數(shù)據(jù)說(shuō)明膳食補(bǔ)充類胡蘿卜素對(duì)心血管疾病的作用，從而促使我們關(guān)注飲食中這些類胡蘿卜素（β-胡蘿卜素，α-胡蘿卜素，β-隱黃質(zhì)，番茄紅素，葉黃素，玉米黃質(zhì)和蝦青素）。
Dietary intake of carotenoids and their antioxidant and anti-inflammatory effects in cardiovascular care
Cardiovascular disease related to atherosclerosis represents nowadays the largest cause of morbidity and mortality in developed countries. Due to inflammatory nature of atherosclerosis, several studies had been conducted in order to search for substances with anti-inflammatory activity on arterial walls, able to exert beneficial roles on health. Researches investigated the role of dietary carotenoids supplementation on cardiovascular disease, due to their free radicals scavenger properties and their skills in improving low-density lipoprotein cholesterol resistance to oxidation. Nevertheless, literature data are conflicting: although some studies found a positive relationship between carotenoids supplementation and cardiovascular risk reduction, others did not find any positive effects or even prooxidant actions. This paper aimed at defining the role of carotenoids supplementation on cardiovascular risk profile by reviewing literature data, paying attention to those carotenoids more present in our diet (β-carotene, α-carotene, β-cryptoxanthin, lycopene, lutein, zeaxanthin, and astaxanthin).
Ciccone MM, Cortese F, Gesualdo M, Carbonara S, Zito A, RicciG, De Pascalis F, Scicchitano P, Riccioni G.
Mediators Inflamm. 2013, 2013:782137.
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